{"id":15679,"date":"2022-08-03T00:00:00","date_gmt":"2022-08-03T00:00:00","guid":{"rendered":"https:\/\/cms.alj3.clients.lemonhq.io\/perspectives\/kanser-tedavisi-icin-yeni-bir-model-olusturmak\/"},"modified":"2026-05-12T13:27:07","modified_gmt":"2026-05-12T13:27:07","slug":"kanser-tedavisi-icin-yeni-bir-model-olusturmak","status":"publish","type":"perspectives","link":"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/perspectives\/kanser-tedavisi-icin-yeni-bir-model-olusturmak\/","title":{"rendered":"Kanser tedavisi i\u00e7in yeni bir model olu\u015fturmak"},"content":{"rendered":"<p><em>Republished from Abdul Latif Jameel Health Insights <a href=\"https:\/\/aljhealth.com\/en\/insights\/forging-a-new-model-for-cancer-treatment-a-qa-with-professor-r-charles-coombes\/\" target=\"_blank\" rel=\"noopener\">here<\/a>.<\/em><\/p>\n<h4>A Q&amp;A with Professor R Charles Coombes, newly appointed special scientific advisor to Abdul Latif Jameel Health<\/h4>\n<p><em>The latest special scientific advisor to join the Advisory Board of <\/em><a href=\"https:\/\/aljhealth.com\"><em>Abdul Latif Jameel Health<\/em><\/a><em> is <\/em><a href=\"https:\/\/aljhealth.com\/en\/our-people\/professor-charles-coombes-mbbs-frcp-md-fmedsci\/\"><em>Professor Charles Coombes<\/em><\/a><em>, a renowned world-leading authority on cancer, with a particular focus on breast cancer. \u00a0We spoke to Professor Coombes about his research, his new role at Abdul Latif Jameel Health, and his vision for the future of global healthcare.<\/em><\/p>\n<p>As part of its mission to accelerate access to modern quality healthcare around the world, Abdul Latif Jameel Health is continually looking to build partnerships with the leading innovators, organizations, and researchers in the global healthcare industry.<\/p>\n<div id=\"attachment_100919\" style=\"width: 1010px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-100919\" class=\"size-full wp-image-100919\" src=\"https:\/\/media.alj.com\/app\/uploads\/2022\/08\/Prof-Charles-Coombes-3.jpg\" alt=\"\" width=\"1000\" height=\"667\" \/><p id=\"caption-attachment-100919\" class=\"wp-caption-text\">Professor Charles Coombes PhD MBBS FRCP MD FMedSci<\/p><\/div>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-100905\" src=\"https:\/\/media.alj.com\/app\/uploads\/2022\/08\/ICR-ICL-logos-300x55.jpg\" alt=\"\" width=\"300\" height=\"55\" \/>Professor R Charles Coombes is Professor of Medical Oncology, <a href=\"https:\/\/www.imperial.ac.uk\/people\/c.coombes\">Imperial College London<\/a>, and Honorary Consultant Medical Oncologist at <a href=\"https:\/\/www.imperial.nhs.uk\/consultant-directory\/raoul-charles-coombes\">Imperial College Healthcare Trust<\/a>.<\/p>\n<p>He is also Chairman of the <a href=\"https:\/\/www.bigagainstbreastcancer.org\/\">International Collaborative Cancer Group<\/a> \u2013 a multinational trial center (based at Imperial College London) focusing on phase II and III studies in breast cancer, among other senior roles in oncology.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-100898\" src=\"https:\/\/media.alj.com\/app\/uploads\/2022\/08\/CRUK-logo-300x87.jpg\" alt=\"\" width=\"300\" height=\"87\" \/>A keen advocate of a cross-disciplinary approach to cancer research, Professor Coombes helped to establish the <a href=\"https:\/\/www.convergencesciencecentre.ac.uk\/\">Convergence Science Centre<\/a> at Imperial College in 2020.<\/p>\n<p>He also runs a translational laboratory which focuses on detection of micro-metastatic disease and application to the treatment of breast cancer.<\/p>\n<h2>Could you provide a brief overview of your current work?<\/h2>\n<p><strong>CC: <\/strong>One of the most important initiatives I\u2019m involved with at the moment is the Convergence Science Centre, which is a strategic partnership between <a href=\"https:\/\/www.imperial.ac.uk\/\">Imperial College London<\/a> and <a href=\"https:\/\/www.icr.ac.uk\/\">The Institute of Cancer Research, London<\/a>, that was initiated around seven years ago.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-100912\" src=\"https:\/\/media.alj.com\/app\/uploads\/2022\/08\/ICR-ICL-exterior-300x195.jpg\" alt=\"\" width=\"300\" height=\"195\" \/>The aim of the program is to bring together the science expertise of Imperial College across a whole range of disciplines to help people with cancer.<\/p>\n<p>The most common sciences used in cancer detection and treatment are molecular and cell biology and drug discovery, but it\u2019s now widely recognized that this isn\u2019t enough.<\/p>\n<p>To truly make headway with this complex disease, you need to leverage the latest expertise from other scientific fields, too, such as bioengineering, mathematics, physics, population sciences, computing sciences, and so forth, which have traditionally been neglected in cancer research.<\/p>\n<p>This work was built on the fact that I\u2019ve spent half of my career at The Institute of Cancer Research and The Royal Marsden Hospital in London, and half my career at Imperial College.\u00a0 It seemed logical \u00a0that if we could bring together these two great institutions, both of which, combined, probably rank among the top in the UK \u2013 if not the world \u2013 in terms of cancer expertise, it could help us solve this problem.<\/p>\n<h2>Could you explain how the Convergence Science Centre works?<\/h2>\n<p><strong>CC: <\/strong>It\u2019s a sad fact that although cancer affects nearly half of us, in the West at least, it\u2019s not easy to predict which person is going to develop what cancer.\u00a0 And if cancer does develop, it\u2019s not easy to predict how the cancer is going to evolve in the human body. \u00a0This uncertainty means we can\u2019t harness new molecular treatments and diagnostic technology in the best way.\u00a0 We now have blood tests and sputum tests that can detect cancer at an extremely early stage, and blood tests that can tell you how the cancer is evolving in the patient.\u00a0 But until we have ways of enriching these technologies, we cannot refine them to be available to everyone in the world.<\/p>\n<p>The Convergence Science Centre helps to bring multiple scientific disciplines together to try and bridge some of these gaps in crucial areas, such as the extremely complex mathematics around genetics and DNA.<\/p>\n<h2>What are the benefits of this approach?<\/h2>\n<p><strong>CC: <\/strong>Cancer treatment in the West is based on a set of rather toxic treatments such as radiotherapy \u00a0and cytotoxic chemotherapy, and so forth.\u00a0 These are ill-defined and non-targeted technologies that as well as combating cancer, are also damaging to normal cells.\u00a0 For the \u2018global south\u2019, the aim is to sidestep these, potentially rather harmful, treatments and go straight to the latest modern diagnostic and therapeutic approaches.\u00a0 For example, artificial intelligence can define which patients need to be screened, and the type of cancer and the evolution of the cancer can all be diagnosed by\u00a0 blood tests.\u00a0 You don\u2019t need complex radiotherapy systems and large healthcare infrastructures.\u00a0 What we will need in the future are usable diagnostic technologies and targeted treatments that will enable us to avoid the sorts of damaging treatments that people have had to undergo to have their cancer treated over the last 50 years.<\/p>\n<p>The combination of easy diagnostics and then targeted treatment following surgery is the answer to improving the survival rate of cancer in the global south.<\/p>\n<h2>When did you first become aware of Abdul Latif Jameel Health?<\/h2>\n<p><strong>CC: <\/strong>It is a name I\u2019ve known for a while \u2013 an organization that I knew was interested in improving access to quality healthcare in emerging markets in the Middle East, Africa and Asia, which is an issue I care deeply about.\u00a0 I regularly attend conferences and I\u2019m invited to give lectures in locations across the world, particularly the MENA region, and Abdul Latif Jameel is a name that often comes up.\u00a0 So, when the opportunity arose to get involved more directly, I was keen to learn more.<\/p>\n<h2>In your role as a special scientific advisor, what do you hope to bring to the organization?<\/h2>\n<p><strong>CC: <\/strong>I\u2019m a cancer clinician and cancer scientist.\u00a0 There is a big gap between what people discover in laboratories and how it\u2019s brought into clinical use and then applied to patients.\u00a0 This gap is often ignored, because scientists are always moving on to the next thing, the next stage in their research, to constantly refine and improve what they\u2019ve done.<\/p>\n<p>It needs somebody like me at Imperial College to take what they\u2019ve developed and say <em>\u201cI know you\u2019re still working on this, but what you\u2019ve got so far looks pretty good.\u00a0 There\u2019s nothing like it out there, so let\u2019s see if we can use it to help people.\u201d<\/em>\u00a0 It\u2019s what I\u2019ve been doing all my career.\u00a0 I\u2019ve been involved in developing new drugs for cancer, new diagnostic tests, mainly for breast cancer, for 40 years, and that\u2019s what I\u2019m aiming to continue doing through my role at Abdul Latif Jameel Health.<\/p>\n<h2>Abdul Latif Jameel Health has a particular focus on improving access to healthcare in the global south. \u00a0Is this important to you?<\/h2>\n<p><strong>CC: <\/strong>Yes, absolutely.\u00a0 It\u2019s an issue I\u2019m passionate about.\u00a0 For example, I\u2019ve lectured in Nigeria where there was a single cancer center with functioning equipment for the entire country of 160 million people.\u00a0 I\u2019ve been to many countries in the region where there is huge poverty, inequality, and a lack of diagnostic capability.<\/p>\n<p>As well as financial hurdles to overcome, there are often cultural ones, too, in terms of educating people about cancer and helping them to understand that it\u2019s not something to be ashamed of or embarrassed about.<\/p>\n<h2>What do you see as the biggest challenges for cancer research and treatment?<\/h2>\n<p><strong>CC: <\/strong>I think education is the most important thing.\u00a0 You could invest any amount of money, but without education it is only going to have a limited impact.\u00a0 The first thing to do is to educate people about illnesses and what can be done about them.\u00a0 The next priority is screening people at risk and introducing some sort of clear pathway for them to get help easily.\u00a0 To a certain degree, a lot of this could be done remotely using modern technology.\u00a0 The idea of people having to travel hundreds of miles and wait for hours in a hospital in the hope of seeing a doctor doesn\u2019t work in the modern world.<\/p>\n<p>One thing the COVID-19 pandemic taught us is that communication across the world is much easier than we thought.\u00a0 We should be using this to our advantage to make healthcare much more accessible in those markets that most need it.<\/p>\n<h2>How could technologies like artificial intelligence and big data help to improve this picture?<\/h2>\n<p><strong>CC: <\/strong>These kinds of technologies are hugely important to the fight against cancer, and increasingly so. Artificial intelligence (AI) is sometimes spoken of as if it\u2019s some sort of separate discipline, but it\u2019s not.\u00a0 It\u2019s already integrated within the work that \u00a0I and many cancer researchers do.<\/p>\n<p>Half the scientists we employ now are specialists in AI. \u00a0Not just talented mathematicians, but people who also understand genetics, biology, cancer, who can bridge these divides and bring that knowledge together.\u00a0 This is modern cancer research, and this is what the Convergence Science Centre aims to do.<\/p>\n<div id=\"attachment_100891\" style=\"width: 1922px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-100891\" class=\"size-full wp-image-100891\" src=\"https:\/\/media.alj.com\/app\/uploads\/2022\/08\/Cells.jpg\" alt=\"\" width=\"1912\" height=\"843\" \/><p id=\"caption-attachment-100891\" class=\"wp-caption-text\">Photo Credit \u00a9 Cancer Research UK Imperial Centre<\/p><\/div>\n<p>A single cell is probably more complex than all the computers currently available throughout the world. \u00a0Within a tiny teaspoon of blood from a cancer patient, there are more than a million fragments of DNA and RNA, all of which give information about the type of cancer they\u2019ve got and how to treat that cancer.\u00a0 But decoding that information and making it sense of it all is impossible without AI.\u00a0 Working out which sub-populations have a greater propensity to develop cancer and therefore more likely to benefit from screening is another critical area where AI is essential.\u00a0 \u00a0And then of course, there are the families with a history of cancer where AI is vital for helping us to understand the genetics of cancer predisposition.<\/p>\n<p>Another area where AI is essential is in terms of chemistry and target identification.\u00a0 When, for example, a blood test shows there is cancer present and that it is growing and dividing by a certain type of factor, to build a drug to inhibit that you need to know the structure of the protein that the drug is supposed to bind to, to inhibit the cancer proliferation in that particular patient.\u00a0 It\u2019s extraordinarily complex and relies on AI at virtually every stage in the journey to discover a new drug.<\/p>\n<h2>How has the pandemic changed the narrative around global healthcare?<\/h2>\n<p><strong>CC: <\/strong>I think it has changed it in two main ways.\u00a0 First, it has shown people that science can have a global impact.\u00a0 There\u2019s been a certain amount of cynicism about modern science among commentators before the pandemic, around climate change for example.\u00a0 The pandemic has shown the massively positive impact that science can have and how it can improve health outcomes for people across the globe.<\/p>\n<p>The second big change is that the pandemic has highlighted the inequality of healthcare between different regions of the world.\u00a0 The proportion of people in the global south who have been vaccinated is still incredibly low, for example.<\/p>\n<p>Within the field of cancer specifically, there is growing understanding that, in the same way that viruses evolve and change their genetics to overcome treatments, cancer does too.\u00a0 \u00a0People have become used to the idea of sequencing viruses and the same thing is true in cancer.\u00a0 You need to monitor the cancer in the patient to predict what treatments you\u2019re going to give the patient.\u00a0 That\u2019s very similar to the development of vaccines for mutated viruses.<\/p>\n<h2>How do you hope Abdul Latif Jameel Health can help to improve this picture and address some of these challenges?<\/h2>\n<p><strong>CC: <\/strong>I believe Abdul Latif Jameel Health has a fairly unique role in that it is interested in early diagnosis, and it seeks to bring the latest healthcare advances to underserved markets in the global south.\u00a0 The Butterfly iQ+ <a href=\"https:\/\/alj.com\/en\/perspective\/democratizing-healthcare-scan-by-scan\/\">handheld ultrasound device<\/a>, for example, is an example of a technology that could make a huge difference in many markets though earlier diagnosis.<\/p>\n<div id=\"attachment_94225\" style=\"width: 2570px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-94225\" class=\"size-full wp-image-94225\" src=\"https:\/\/media.alj.com\/app\/uploads\/2021\/11\/ERM_4668.jpg\" alt=\"Butterfly Network\" width=\"2560\" height=\"1707\" \/><p id=\"caption-attachment-94225\" class=\"wp-caption-text\">The Butterfly IQ+ hand-held, whole-body ultrasound probe in action (Photo Credit \u00a9 Butterfly Network Inc.)<\/p><\/div>\n<p>Abdul Latif Jameel\u2019s strong legacy in the region, its knowledge, understanding and existing partnerships, can also be a great advantage in getting these technologies out into the market and overcoming some of the barriers \u2013 often cultural and practical issues as much as financial ones.<\/p>\n<h2>Looking ahead, how optimistic are you for the future of cancer research and cancer treatment?<\/h2>\n<p><strong>CC: <\/strong>I\u2019m biased, because in my area of breast cancer I\u2019ve seen the cure rate improving quite dramatically throughout my career, so in that sense I\u2019m very optimistic.\u00a0 Of course, there are still big discrepancies in breast cancer rates across the globe, but overall, I\u2019m hopeful that in 10 years we will have significantly improved the cure rate.<\/p>\n<p>Other cancers, like lung cancer, pancreatic cancer, brain cancer, stomach cancer for example, are very difficult to treat, partly because they are diagnosed too late.\u00a0 This is where some of these technologies around testing, screening and early diagnosis are vital.\u00a0 These could change the face of cancer treatment, particularly in the global south, if we can apply them effectively.<\/p>\n<p>So, I\u2019m optimistic, but it needs to be done on almost an \u2018industrial\u2019 scale rather than the piecemeal methods that have been used up to now.<\/p>\n","protected":false},"featured_media":15663,"menu_order":0,"template":"","class_list":["post-15679","perspectives","type-perspectives","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Kanser tedavisi i\u00e7in yeni bir model olu\u015fturmak - Abdul Latif Jameel<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Kanser tedavisi i\u00e7in yeni bir model olu\u015fturmak - Abdul Latif Jameel\" \/>\n<meta property=\"og:description\" content=\"Republished from Abdul Latif Jameel Health Insights here. A Q&amp;A with Professor R Charles Coombes, newly appointed special scientific advisor to Abdul Latif Jameel Health The latest special scientific advisor to join the Advisory Board of Abdul Latif Jameel Health is Professor Charles Coombes, a renowned world-leading authority on cancer, with a particular focus on [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/perspectives\/kanser-tedavisi-icin-yeni-bir-model-olusturmak\/\" \/>\n<meta property=\"og:site_name\" content=\"Abdul Latif Jameel\" \/>\n<meta property=\"article:modified_time\" content=\"2026-05-12T13:27:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/Cancer-Cells-Illustration.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1546\" \/>\n\t<meta property=\"og:image:height\" content=\"1032\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data1\" content=\"11 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/perspectives\/kanser-tedavisi-icin-yeni-bir-model-olusturmak\/\",\"url\":\"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/perspectives\/kanser-tedavisi-icin-yeni-bir-model-olusturmak\/\",\"name\":\"Kanser tedavisi i\u00e7in yeni bir model olu\u015fturmak - Abdul Latif Jameel\",\"isPartOf\":{\"@id\":\"https:\/\/10.0.2.222\/en\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/perspectives\/kanser-tedavisi-icin-yeni-bir-model-olusturmak\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/perspectives\/kanser-tedavisi-icin-yeni-bir-model-olusturmak\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/Cancer-Cells-Illustration.jpg\",\"datePublished\":\"2022-08-03T00:00:00+00:00\",\"dateModified\":\"2026-05-12T13:27:07+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/perspectives\/kanser-tedavisi-icin-yeni-bir-model-olusturmak\/#breadcrumb\"},\"inLanguage\":\"tr\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/perspectives\/kanser-tedavisi-icin-yeni-bir-model-olusturmak\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"tr\",\"@id\":\"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/perspectives\/kanser-tedavisi-icin-yeni-bir-model-olusturmak\/#primaryimage\",\"url\":\"https:\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/Cancer-Cells-Illustration.jpg\",\"contentUrl\":\"https:\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/Cancer-Cells-Illustration.jpg\",\"width\":1546,\"height\":1032},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/perspectives\/kanser-tedavisi-icin-yeni-bir-model-olusturmak\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/10.0.2.222\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Kanser tedavisi i\u00e7in yeni bir model olu\u015fturmak\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/10.0.2.222\/en\/#website\",\"url\":\"https:\/\/10.0.2.222\/en\/\",\"name\":\"Abdul Latif Jameel\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/10.0.2.222\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"tr\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Kanser tedavisi i\u00e7in yeni bir model olu\u015fturmak - Abdul Latif Jameel","robots":{"index":"noindex","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"og_locale":"tr_TR","og_type":"article","og_title":"Kanser tedavisi i\u00e7in yeni bir model olu\u015fturmak - Abdul Latif Jameel","og_description":"Republished from Abdul Latif Jameel Health Insights here. 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Charles Coombes ile bir Soru-Cevap oturumu<\/p>"],"_mobile_featured_image":["field_66f6b4bee65f3"],"mobile_featured_image":["https:\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/Cancer-Cells-Illustration.jpg"],"_push_notification":["field_66f6b47de65f1"],"push_notification":[""],"_publish_mobile":["field_66f6b491e65f2"],"publish_mobile":["0"],"_status":["field_652694983fe12"],"status":["publish"],"_thumbnail_id":["15663"],"_wpml_word_count":["{\"total\":1722,\"to_translate\":{\"ar\":1722,\"zh-hans\":1722,\"fr\":1722,\"ja\":1722,\"es\":1722,\"tr\":1722}}"],"_last_translation_edit_mode":["native-editor"],"amazonS3_cache":["a:18:{s:83:\"\/\/cms.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/Prof-Charles-Coombes-3.jpg\";a:2:{s:2:\"id\";s:5:\"15664\";s:11:\"source_type\";s:13:\"media-library\";}s:85:\"\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/Prof-Charles-Coombes-3.jpg\";a:2:{s:2:\"id\";s:5:\"15664\";s:11:\"source_type\";s:13:\"media-library\";}s:74:\"\/\/cms.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/ICR-ICL-logos.jpg\";a:2:{s:2:\"id\";s:5:\"15665\";s:11:\"source_type\";s:13:\"media-library\";}s:81:\"\/\/cms.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/ICR-ICL-logos-300x55.jpg\";a:2:{s:2:\"id\";s:5:\"15665\";s:11:\"source_type\";s:13:\"media-library\";}s:76:\"\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/ICR-ICL-logos.jpg\";a:2:{s:2:\"id\";s:5:\"15665\";s:11:\"source_type\";s:13:\"media-library\";}s:83:\"\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/ICR-ICL-logos-300x55.jpg\";a:2:{s:2:\"id\";s:5:\"15665\";s:11:\"source_type\";s:13:\"media-library\";}s:70:\"\/\/cms.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/CRUK-logo.jpg\";a:2:{s:2:\"id\";s:5:\"15666\";s:11:\"source_type\";s:13:\"media-library\";}s:77:\"\/\/cms.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/CRUK-logo-300x87.jpg\";a:2:{s:2:\"id\";s:5:\"15666\";s:11:\"source_type\";s:13:\"media-library\";}s:72:\"\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/CRUK-logo.jpg\";a:2:{s:2:\"id\";s:5:\"15666\";s:11:\"source_type\";s:13:\"media-library\";}s:79:\"\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/CRUK-logo-300x87.jpg\";a:2:{s:2:\"id\";s:5:\"15666\";s:11:\"source_type\";s:13:\"media-library\";}s:77:\"\/\/cms.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/ICR-ICL-exterior.jpg\";a:2:{s:2:\"id\";s:5:\"15667\";s:11:\"source_type\";s:13:\"media-library\";}s:85:\"\/\/cms.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/ICR-ICL-exterior-300x195.jpg\";a:2:{s:2:\"id\";s:5:\"15667\";s:11:\"source_type\";s:13:\"media-library\";}s:79:\"\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/ICR-ICL-exterior.jpg\";a:2:{s:2:\"id\";s:5:\"15667\";s:11:\"source_type\";s:13:\"media-library\";}s:87:\"\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/ICR-ICL-exterior-300x195.jpg\";a:2:{s:2:\"id\";s:5:\"15667\";s:11:\"source_type\";s:13:\"media-library\";}s:66:\"\/\/cms.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/Cells.jpg\";a:2:{s:2:\"id\";s:5:\"15668\";s:11:\"source_type\";s:13:\"media-library\";}s:68:\"\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/Cells.jpg\";a:2:{s:2:\"id\";s:5:\"15668\";s:11:\"source_type\";s:13:\"media-library\";}s:69:\"\/\/cms.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/ERM_4668.jpg\";a:2:{s:2:\"id\";s:4:\"3984\";s:11:\"source_type\";s:13:\"media-library\";}s:71:\"\/\/media.alj3.clients.lemonhq.io\/wp-content\/uploads\/2024\/10\/ERM_4668.jpg\";a:2:{s:2:\"id\";s:4:\"3984\";s:11:\"source_type\";s:13:\"media-library\";}}"],"_edit_lock":["1778592508:22"],"content":["<h4>Abdul Latif Jameel Health\u2019e \u00f6zel bilimsel dan\u0131\u015fman olarak yeni atanan Profes\u00f6r R. Charles Coombes ile bir Soru-Cevap oturumu<\/h4>\r\n<p><em>\u00d6zel olarak odakland\u0131\u011f\u0131 meme kanseri alan\u0131ndaki \u00e7al\u0131\u015fmalar\u0131yla kanser alan\u0131nda d\u00fcnyaya \u00f6nc\u00fcl\u00fck eden ve tan\u0131nm\u0131\u015f bir otorite olan <\/em><a href=\"https:\/\/aljhealth.com\/en\/our-people\/professor-charles-coombes-mbbs-frcp-md-fmedsci\/\"><em>Profes\u00f6r Charles Coombes<\/em><\/a><em>, <\/em><a href=\"https:\/\/aljhealth.com\"><em>Abdul Latif Jameel Health<\/em><\/a><em> Dan\u0131\u015fma Kuruluna en son kat\u0131lan \u00f6zel bilimsel dan\u0131\u015fmand\u0131r. Profes\u00f6r Coombes ile ara\u015ft\u0131rmalar\u0131, Abdul Latif Jameel Health\u2019teki yeni g\u00f6revi ve k\u00fcresel sa\u011fl\u0131k hizmetinin gelece\u011fine ili\u015fkin vizyonu hakk\u0131nda konu\u015ftuk.<\/em><\/p>\r\n<p>Abdul Latif Jameel Health, d\u00fcnya genelinde modern sa\u011fl\u0131k hizmetlerine eri\u015filebilirli\u011fi h\u0131zland\u0131rma misyonunun bir par\u00e7as\u0131 olarak, biyoteknoloji ve sa\u011fl\u0131k sekt\u00f6rlerindeki \u00f6nde gelen k\u00fcresel kurulu\u015flar, ara\u015ft\u0131rmac\u0131lar ve d\u00fc\u015f\u00fcn\u00fcrlerle s\u00fcrekli olarak ortakl\u0131klar olu\u015fturmay\u0131 hedefler.<\/p>\r\n\r\n[caption id=\"attachment_100925\" align=\"aligncenter\" width=\"1000\"]<img class=\"size-full wp-image-100925\" src=\"https:\/\/alj.com\/app\/uploads\/2022\/08\/Prof-Charles-Coombes-3.jpg\" alt=\"\" width=\"1000\" height=\"667\" \/> Doktora derecesi, t\u0131p ve cerrahi lisans derecesi, federal us\u00fcl kuralar\u0131 y\u00fcksek lisans derecesi sahibi ve T\u0131bbi Kurul \u00dcyesi olan Profes\u00f6r Charles Coombes[\/caption]\r\n\r\n<p><img class=\"alignright size-medium wp-image-100911\" src=\"https:\/\/alj.com\/app\/uploads\/2022\/08\/ICR-ICL-logos-300x55.jpg\" alt=\"\" width=\"300\" height=\"55\" \/>Profes\u00f6r R. Charles Coombes T\u0131bbi Onkoloji Profes\u00f6r\u00fc olarak <a href=\"https:\/\/www.imperial.ac.uk\/people\/c.coombes\">Imperial College London<\/a>\u2019da ve Fahri Dan\u0131\u015fman T\u0131bbi Onkolog olarak <a href=\"https:\/\/www.imperial.nhs.uk\/consultant-directory\/raoul-charles-coombes\">Imperial College Healthcare Trust<\/a>\u2019ta g\u00f6rev yap\u0131yor.<\/p>\r\n<p><img class=\"alignleft size-medium wp-image-100904\" src=\"https:\/\/alj.com\/app\/uploads\/2022\/08\/CRUK-logo-300x87.jpg\" alt=\"\" width=\"300\" height=\"87\" \/>Onkoloji alan\u0131ndaki di\u011fer \u00fcst d\u00fczey g\u00f6revlerinin yan\u0131 s\u0131ra meme kanseri ile ilgili faz II ve III \u00e7al\u0131\u015fmalara odaklanan \u00e7ok uluslu bir \u00e7al\u0131\u015fma merkezi olan ve Imperial College London\u2019da bulunan <a href=\"https:\/\/www.bigagainstbreastcancer.org\/\">Uluslararas\u0131 Kanser \u0130\u015f Birli\u011fi Grubu<\/a>\u2019nun ba\u015fkan\u0131d\u0131r.<\/p>\r\n<p>Kanser ara\u015ft\u0131rmalar\u0131nda disiplinler aras\u0131 yakla\u015f\u0131m\u0131n tutkulu bir savunucusu olan Profes\u00f6r Coombes, <a href=\"https:\/\/www.convergencesciencecentre.ac.uk\/\">Convergence Science Centre<\/a><u>\u2019\u0131n <\/u>2020 y\u0131l\u0131nda Imperial College\u2019da kurulmas\u0131na yard\u0131mc\u0131 oldu.<\/p>\r\n<p>Ayr\u0131ca, mikrometastatik hastal\u0131\u011f\u0131n saptanmas\u0131na ve meme kanserinin tedavi uygulamalar\u0131na odaklanan d\u00f6n\u00fc\u015ft\u00fcr\u00fclebilir bir laboratuvar\u0131n faaliyetlerini de y\u00fcr\u00fctmektedir.\u00a0<\/p>\r\n<h2>Mevcut \u00e7al\u0131\u015fmalar\u0131n\u0131zdan k\u0131saca bahsedebilir misiniz?<\/h2>\r\n<p><strong><img class=\"alignright size-medium wp-image-100918\" src=\"https:\/\/alj.com\/app\/uploads\/2022\/08\/ICR-ICL-exterior-300x195.jpg\" alt=\"\" width=\"300\" height=\"195\" \/>CC: <\/strong>\u015eu anda dahil oldu\u011fum en \u00f6nemli giri\u015fimlerden biri Convergence Science Centre\u2019d\u0131r. Bu program yakla\u015f\u0131k yedi y\u0131l \u00f6nce <a href=\"https:\/\/www.imperial.ac.uk\/\">Imperial College London<\/a> ve <a href=\"https:\/\/www.icr.ac.uk\/\">The Institute of Cancer Research, London<\/a> aras\u0131nda ba\u015flat\u0131lm\u0131\u015ft\u0131r.<\/p>\r\n<p>Program, kanserli insanlara yard\u0131mc\u0131 olmak amac\u0131yla Imperial College\u2019\u0131n bilim uzmanl\u0131\u011f\u0131n\u0131 \u00e7e\u015fitli disiplinlerle bir araya getiriyor.<\/p>\r\n<p>Kanser te\u015fhisi ve tedavisinde en yayg\u0131n olarak kullan\u0131lan bilimler, molek\u00fcler ve h\u00fccre biyolojisi ve ila\u00e7 ke\u015ffidir. Ancak bunun yeterli olmad\u0131\u011f\u0131 art\u0131k yayg\u0131n olarak kabul ediliyor.<\/p>\r\n<p>Bu karma\u015f\u0131k hastal\u0131kla ger\u00e7ekten ba\u015fa \u00e7\u0131kmak i\u00e7in geleneksel kanser ara\u015ft\u0131rmalar\u0131nda ihmal edilmi\u015f biyom\u00fchendislik, matematik, fizik, n\u00fcfus bilimleri, bilgi i\u015flem bilimleri gibi di\u011fer bilimsel alanlardaki en g\u00fcncel uzmanl\u0131klardan da yararlanman\u0131z gerekiyor.<\/p>\r\n<p>Bu \u00e7al\u0131\u015fma, kariyerimin yar\u0131s\u0131n\u0131 ge\u00e7irdi\u011fim Londra\u2019daki Kanser Ara\u015ft\u0131rma Enstit\u00fcs\u00fc\u2019nde ve Royal Marsden Hastanesi\u2019nde ve kariyerimin di\u011fer yar\u0131s\u0131n\u0131 ge\u00e7irdi\u011fim Imperial College\u2019da edindi\u011fim deneyimleri temel al\u0131yor. D\u00fcnyada olmasa bile Birle\u015fik Krall\u0131k\u2019ta muhtemelen ilk s\u0131ralarda yer alan ve kanser uzmanl\u0131\u011f\u0131 a\u00e7\u0131s\u0131ndan bu sorunu \u00e7\u00f6zmemize yard\u0131mc\u0131 olabilecek bu iki harika kurumu bir araya getirebilmemiz mant\u0131kl\u0131 g\u00f6r\u00fcn\u00fcyordu.<\/p>\r\n<h2>Convergence Science Centre\u2019\u0131n nas\u0131l \u00e7al\u0131\u015ft\u0131\u011f\u0131n\u0131 a\u00e7\u0131klayabilir misiniz?<\/h2>\r\n<p><strong>CC: <\/strong>Bat\u0131 d\u00fcnyas\u0131nda kanser hastal\u0131\u011f\u0131n\u0131n insanlar\u0131n neredeyse yar\u0131s\u0131n\u0131 etkilemesi \u00fcz\u00fcc\u00fc bir ger\u00e7ek olsa da kimin hangi kansere yakalanaca\u011f\u0131n\u0131 tahmin etmek kolay de\u011fil. Kansere yakaland\u0131\u011f\u0131m\u0131zda kanserin insan v\u00fccudunda nas\u0131l ilerleyece\u011fini tahmin etmek de zor. Bu belirsizlik, yeni molek\u00fcler tedavileri ve te\u015fhis teknolojilerini en iyi \u015fekilde kullanamayaca\u011f\u0131m\u0131z anlam\u0131na geliyor. \u015eimdi, kanseri olduk\u00e7a erken bir a\u015famada tespit edebilen ve kanserin hastada nas\u0131l ilerleyece\u011fini g\u00f6sterebilen kan testlerine ve balgam testlerine sahibiz. Ne yaz\u0131k ki bu teknolojileri geli\u015ftirmenin yollar\u0131n\u0131 bulana kadar, bunlar\u0131 d\u00fcnyadaki herkesin kullan\u0131m\u0131na sunabilecek hale getiremeyiz.<\/p>\r\n<p>Convergence Science Centre, genetik ve DNA alan\u0131nda son derece karma\u015f\u0131k matematik y\u00f6ntemler gibi \u00f6nemli alanlardaki bu bo\u015fluklar\u0131n baz\u0131lar\u0131n\u0131 doldurmak ve aralar\u0131nda ba\u011flant\u0131 kurmak i\u00e7in birden fazla bilimsel disiplini bir araya getirmeye yard\u0131mc\u0131 oluyor.<\/p>\r\n<h2>Bu yakla\u015f\u0131m\u0131n faydalar\u0131 nelerdir?<\/h2>\r\n<p><strong>CC: <\/strong>Bat\u0131\u2019da uygulanan kanser tedavisi, radyoterapi ve sitotoksik kemoterapi gibi olduk\u00e7a toksik tedavilere dayan\u0131r. Bunlar bir yandan kanserle m\u00fccadele ederken di\u011fer yandan normal h\u00fccrelere de zarar veren, iyi tan\u0131mlanmam\u0131\u015f ve hedef d\u0131\u015f\u0131na \u00e7\u0131kabilen teknolojilerdir. \u201cGeli\u015fmekte olan \u00fclkelerde\u201d ama\u00e7, potansiyel olarak zararl\u0131 olan bu tedavileri atlay\u0131p do\u011frudan en yeni modern tan\u0131sal ve terap\u00f6tik yakla\u015f\u0131mlara ge\u00e7mektir. \u00d6rne\u011fin yapay zeka, hangi hastalar\u0131n taranmas\u0131 gerekti\u011fini tan\u0131mlayabilir ve kanser t\u00fcr\u00fcn\u00fc ve kanserin ilerleme seviyesini te\u015fhis edebilir. Karma\u015f\u0131k radyoterapi sistemlerine ve b\u00fcy\u00fck sa\u011fl\u0131k hizmetleri altyap\u0131lar\u0131na ihtiyac\u0131n\u0131z yoktur. Gelecekte ihtiya\u00e7 duyaca\u011f\u0131m\u0131z \u015fey, insanlar\u0131n son 50 y\u0131lda mecburen kulland\u0131klar\u0131 zarar verici kanser tedavisi y\u00f6ntemlerinden ka\u00e7\u0131nmam\u0131z\u0131 sa\u011flayacak kullan\u0131\u015fl\u0131 tan\u0131 teknolojileri ve hedefe y\u00f6nelik tedavilerdir.<\/p>\r\n<p>Geli\u015fmekte olan \u00fclkelerde kanser sa\u011f kal\u0131m oran\u0131n\u0131 iyile\u015ftirmenin anahtar\u0131, kolay tan\u0131 y\u00f6ntemlerinin ve ameliyattan sonra hedefe y\u00f6nelik tedavinin bir arada kullan\u0131lmas\u0131d\u0131r.<\/p>\r\n<h2>Abdul Latif Jameel Health\u2019ten ilk ne zaman haberdar oldunuz?<\/h2>\r\n<p><strong>CC: <\/strong>\u00c7ok \u00f6nem verdi\u011fim bir konu olan Orta Do\u011fu, Afrika ve Asya\u2019daki geli\u015fmekte olan pazarlarda kaliteli sa\u011fl\u0131k hizmetlerine eri\u015fimi geli\u015ftirmekle ilgilendi\u011fini bildi\u011fim ve bir s\u00fcredir ad\u0131n\u0131 duydu\u011fum bir kurulu\u015f. Ba\u015fta MENA b\u00f6lgesi olmak \u00fczere d\u00fcnyan\u0131n d\u00f6rt bir yan\u0131nda d\u00fczenli olarak konferanslara kat\u0131l\u0131yorum ve ders vermeye davet ediliyorum. Abdul Latif Jameel genellikle buralarda kar\u015f\u0131ma \u00e7\u0131kan bir isimdi. Bu nedenle, bu kurulu\u015fla daha do\u011frudan bir ba\u011flant\u0131 kurma f\u0131rsat\u0131 yakalad\u0131\u011f\u0131mda daha fazla bilgi edinmek istedim.<\/p>\r\n<h2>\u00d6zel bilimsel dan\u0131\u015fman olarak atand\u0131\u011f\u0131n\u0131z g\u00f6revinizde, bu kurulu\u015fa ne t\u00fcr katk\u0131lar sunmay\u0131 umuyorsunuz?<\/h2>\r\n<p><strong>CC: <\/strong>Ben bir klinik kanser ara\u015ft\u0131rmac\u0131s\u0131 ve kanser bilim insan\u0131y\u0131m. \u0130nsanlar\u0131n laboratuvarlarda ke\u015ffettikleri bulgularla, bu bulgular\u0131n klinik kullan\u0131ma nas\u0131l sunuldu\u011fu ve daha sonras\u0131nda hastalara nas\u0131l uyguland\u0131\u011f\u0131 konusunda b\u00fcy\u00fck bir bo\u015fluk var. Bu bo\u015fluk genellikle yok say\u0131l\u0131yor. \u00c7\u00fcnk\u00fc bilim insanlar\u0131 yapt\u0131klar\u0131n\u0131 s\u00fcrekli olarak iyile\u015ftirmek ve geli\u015ftirmek i\u00e7in hep ara\u015ft\u0131rmalar\u0131n\u0131n bir sonraki a\u015famas\u0131na ge\u00e7iyorlar.<\/p>\r\n<p>Imperial College\u2019da benim gibi birinin gelip bu bilim insanlar\u0131n\u0131n geli\u015ftirdikleri bulgular\u0131 al\u0131p <em>\u201cBunun \u00fczerinde hala \u00e7al\u0131\u015ft\u0131\u011f\u0131n\u0131z\u0131 biliyorum ama \u015fimdiye kadar yapt\u0131klar\u0131n\u0131z olduk\u00e7a iyi g\u00f6r\u00fcn\u00fcyor. Buna benzer bir bulgu yok, o y\u00fczden bunu insanlara faydal\u0131 olmas\u0131 i\u00e7in kullan\u0131p kullanamayaca\u011f\u0131m\u0131za bakal\u0131m.\u201d<\/em> demesi gerekiyor. T\u00fcm kariyerim boyunca yapt\u0131\u011f\u0131m \u015fey buydu. 40 y\u0131ld\u0131r, ba\u015fta meme kanseri olmak \u00fczere kanser i\u00e7in yeni ila\u00e7lar ve tan\u0131 testleri geli\u015ftirmekle ilgileniyorum ve Abdul Latif Jameel Health\u2019teki g\u00f6revim arac\u0131l\u0131\u011f\u0131yla bunu yapmaya devam etmeyi hedefliyorum.<\/p>\r\n<h2>Abdul Latif Jameel Health \u00f6zellikle geli\u015fmekte olan \u00fclkelerde sa\u011fl\u0131k hizmetlerine eri\u015fimi geli\u015ftirmeye odaklanm\u0131\u015ft\u0131r. Bu sizin i\u00e7in \u00f6nemli mi?<\/h2>\r\n<p><strong>CC: <\/strong>Evet, kesinlikle. Bu tutkuyla yakla\u015ft\u0131\u011f\u0131m bir sorun. \u00d6rne\u011fin, \u00fclkenin tamam\u0131ndaki 160 milyon insan i\u00e7in i\u015flevsel ekipmanlara sahip tek bir kanser merkezine sahip olan Nijerya\u2019da ders verdim. B\u00f6lgede, \u00e7ok b\u00fcy\u00fck oranda yoksulluk, e\u015fitsizlik ve tan\u0131 kapasitesi eksikli\u011fi ya\u015fanan bir\u00e7ok \u00fclkede \u00e7al\u0131\u015ft\u0131m.<\/p>\r\n<p>\u00dcstesinden gelinmesi gereken finansal engellerin yan\u0131 s\u0131ra insanlar\u0131 kanser hakk\u0131nda e\u011fitmek ve bunun utan\u0131lacak bir \u015fey olmad\u0131\u011f\u0131n\u0131 anlamalar\u0131na yard\u0131mc\u0131 olmak a\u00e7\u0131s\u0131ndan pek \u00e7ok k\u00fclt\u00fcrel engel de var.<\/p>\r\n<h2>Kanser ara\u015ft\u0131rmas\u0131 ve tedavisinde kar\u015f\u0131la\u015f\u0131lan en b\u00fcy\u00fck zorluklar sizce nelerdir?<\/h2>\r\n<p><strong>CC: <\/strong>Bence e\u011fitim en \u00f6nemli \u015fey. \u0130stedi\u011finiz kadar \u00e7ok para yat\u0131rabilirsiniz ancak e\u011fitim olmadan bu yaln\u0131zca s\u0131n\u0131rl\u0131 bir etkiye sahip olur. Yap\u0131lacak ilk \u015fey, insanlar\u0131 hastal\u0131klar ve bunlarla ilgili olarak neler yapabilecekleri hakk\u0131nda e\u011fitmektir. Bir sonraki \u00f6ncelik, risk alt\u0131ndaki ki\u015fileri taramak ve kolayca yard\u0131m alabilecekleri baz\u0131 imkanlar sunmakt\u0131r. Belli bir dereceye kadar, bunlar\u0131n \u00e7o\u011fu modern teknolojiyle uzaktan yap\u0131labilir. \u0130nsanlar\u0131n bir doktora muayene olma umuduyla y\u00fczlerce kilometre seyahat etmesi ve hastanede saatlerce beklemesi fikri, modern d\u00fcnyayla pek uyu\u015fmuyor.<\/p>\r\n<p>COVID-19 k\u00fcresel salg\u0131n\u0131n\u0131n bize \u00f6\u011fretti\u011fi \u015feylerden biri de d\u00fcnya genelinde ileti\u015fimin d\u00fc\u015f\u00fcnd\u00fc\u011f\u00fcm\u00fczden \u00e7ok daha kolay olmas\u0131yd\u0131. Bunu, sa\u011fl\u0131k hizmetini en \u00e7ok ihtiya\u00e7 duyan pazarlarda daha eri\u015filebilir k\u0131lmak i\u00e7in bir avantaj olarak kullanmal\u0131y\u0131z.<\/p>\r\n<h2>Yapay zeka ve b\u00fcy\u00fck veri gibi teknolojiler bu tablonun iyile\u015ftirilmesine nas\u0131l yard\u0131mc\u0131 olabilir?<\/h2>\r\n<p><strong>CC: <\/strong>Bu t\u00fcr teknolojiler kanserle m\u00fccadelede son derece \u00f6nemlidir ve giderek artmaktad\u0131r. Yapay zekadan (AI) bazen sanki ayr\u0131 bir disiplinmi\u015f gibi bahsedilir; ancak \u00f6yle de\u011fildir. Ben ve pek \u00e7ok kanser ara\u015ft\u0131rmac\u0131s\u0131n\u0131n yapt\u0131\u011f\u0131 i\u015fe zaten entegre olmu\u015ftur.<\/p>\r\n<p>\u00c7al\u0131\u015ft\u0131\u011f\u0131m\u0131z bilim insanlar\u0131n\u0131n yar\u0131s\u0131 yapay zeka alan\u0131nda uzmand\u0131r. Sadece yetenekli matematik\u00e7iler de\u011fil; genetik, biyoloji ve kanseri bilen ki\u015filer de bu alanlar aras\u0131nda k\u00f6pr\u00fcler kurarak bilgileri bir araya getirebilir. Modern kanser ara\u015ft\u0131rmas\u0131 budur ve Convergence Science Centre\u2019\u0131n yapmay\u0131 ama\u00e7lad\u0131\u011f\u0131 \u015fey de budur.<\/p>\r\n\r\n[caption id=\"attachment_100897\" align=\"aligncenter\" width=\"1912\"]<img class=\"size-full wp-image-100897\" src=\"https:\/\/alj.com\/app\/uploads\/2022\/08\/Cells.jpg\" alt=\"\" width=\"1912\" height=\"843\" \/> Foto\u011fraf Sahibi \u00a9 Cancer Research UK Imperial Centre[\/caption]\r\n\r\n<p>Tek bir h\u00fccre bile muhtemelen \u015fu anda d\u00fcnya genelinde bulunan t\u00fcm bilgisayarlardan daha karma\u015f\u0131k bir yap\u0131ya sahiptir. Bir kanser hastas\u0131ndan al\u0131nan k\u00fc\u00e7\u00fck bir \u00e7ay ka\u015f\u0131\u011f\u0131 kan\u0131n i\u00e7inde bir milyondan fazla DNA ve RNA par\u00e7as\u0131 vard\u0131r ve bunlar\u0131n t\u00fcm\u00fc, kanser t\u00fcrleri ve bu kanser t\u00fcr\u00fcn\u00fcn nas\u0131l tedavi edilece\u011fi hakk\u0131nda bilgi verebilir. Ancak yapay zeka olmadan bu bilgileri de\u015fifre etmek ve anlamland\u0131rmak m\u00fcmk\u00fcn de\u011fildir. Hangi alt pop\u00fclasyonlar\u0131n kansere yakalanma e\u011filiminin daha y\u00fcksek oldu\u011funu ve dolay\u0131s\u0131yla taramadan fayda sa\u011flama olas\u0131l\u0131\u011f\u0131n\u0131n daha y\u00fcksek oldu\u011funu belirlemek, yapay zekan\u0131n gerekli oldu\u011fu ba\u015fka bir kritik aland\u0131r. Hatta yapay zekay\u0131 kullanarak kanser yatk\u0131nl\u0131\u011f\u0131n\u0131n genetik temellerini anlamam\u0131za yard\u0131mc\u0131 olmas\u0131 a\u00e7\u0131s\u0131ndan hayati \u00f6nem ta\u015f\u0131yan, kanser ge\u00e7mi\u015fine sahip aileler var.<\/p>\r\n<p>Yapay zekan\u0131n temel \u00f6nem ta\u015f\u0131d\u0131\u011f\u0131 bir di\u011fer alan da kimya ve hedef tan\u0131mlamad\u0131r. \u00d6rne\u011fin, bir kan testi, belirli bir hastan\u0131n kanser oldu\u011funu ve kanserin belirli bir fakt\u00f6re g\u00f6re b\u00fcy\u00fcd\u00fc\u011f\u00fcn\u00fc ve b\u00f6l\u00fcnd\u00fc\u011f\u00fcn\u00fc g\u00f6sterdi\u011finde, kanserin yay\u0131lmas\u0131n\u0131 engelleyecek bir ila\u00e7 olu\u015fturmak i\u00e7in ilac\u0131n ba\u011flanmas\u0131 gereken proteinin yap\u0131s\u0131n\u0131 bilmeniz gerekir. Bu s\u00fcre\u00e7 ola\u011fan\u00fcst\u00fc derecede karma\u015f\u0131kt\u0131r ve yeni bir ila\u00e7 ke\u015ffetme yolculu\u011funun neredeyse her a\u015famas\u0131 yapay zekaya dayan\u0131r.<\/p>\r\n<h2>Pandemi, k\u00fcresel sa\u011fl\u0131k hizmetlerini nas\u0131l de\u011fi\u015ftirdi?<\/h2>\r\n<p><strong>CC: <\/strong>Bence iki temel bi\u00e7imde de\u011fi\u015ftirdi. \u0130lk olarak, insanlara bilimin k\u00fcresel bir etkiye sahip olabilece\u011fini g\u00f6sterdi. \u00d6rne\u011fin, pandemiden \u00f6nce iklim de\u011fi\u015fikli\u011fi hakk\u0131nda yorum yapanlar aras\u0131nda modern bilim ile ilgili belirli bir \u015f\u00fcphe vard\u0131. Pandemi, bilimin yaratabilece\u011fi olumlu y\u00f6ndeki b\u00fcy\u00fck etkileri ve insanlar\u0131n sa\u011fl\u0131k sorunlar\u0131n\u0131 d\u00fcnya genelinde nas\u0131l iyile\u015ftirebilece\u011fini g\u00f6sterdi.<\/p>\r\n<p>\u0130kinci b\u00fcy\u00fck de\u011fi\u015fiklik; pandeminin, d\u00fcnyan\u0131n farkl\u0131 b\u00f6lgeleri aras\u0131ndaki sa\u011fl\u0131k hizmeti e\u015fitsizli\u011fini g\u00f6zler \u00f6n\u00fcne sermesi olmu\u015ftur. \u00d6rne\u011fin, geli\u015fmekte olan \u00fclkelerde a\u015f\u0131lanm\u0131\u015f insanlar\u0131n oran\u0131 hala inan\u0131lmaz derecede d\u00fc\u015f\u00fckt\u00fcr.<\/p>\r\n<p>Vir\u00fcslerin evrim ge\u00e7irdi\u011fi ve davran\u0131\u015flar\u0131n\u0131 de\u011fi\u015ftirmek i\u00e7in genetiklerinin de\u011fi\u015ftirildi\u011fi anlay\u0131\u015f\u0131na benzer bir anlay\u0131\u015f da \u00f6zellikle kanser alan\u0131nda gittik\u00e7e yayg\u0131nla\u015f\u0131yor. \u0130nsanlar vir\u00fcs dizileme fikrine al\u0131\u015ft\u0131. Ayn\u0131 \u015fey kanser i\u00e7in de ge\u00e7erli. Hastaya hangi tedavileri verece\u011finizi \u00f6ng\u00f6rmek i\u00e7in hastadaki kanseri izlemeniz gerekir. Bu, mutasyona u\u011fram\u0131\u015f vir\u00fcslere kar\u015f\u0131 a\u015f\u0131 geli\u015ftirmeye \u00e7ok benzer.<\/p>\r\n<h2>Sizce Abdul Latif Jameel Health, bu tablonun iyile\u015ftirmesine ve bu zorluklar\u0131n baz\u0131lar\u0131n\u0131n \u00fcstesinden gelinmesine nas\u0131l yard\u0131mc\u0131 olabilir?<\/h2>\r\n<p><strong>CC: <\/strong>Abdul Latif Jameel Health\u2019in erken te\u015fhisle ilgilenerek olduk\u00e7a benzersiz bir rol \u00fcstlendi\u011fine inan\u0131yorum ve sa\u011fl\u0131k hizmetlerindeki en son geli\u015fmeleri yetersiz hizmet alan, geli\u015fmekte olan \u00fclkelerdeki pazarlara g\u00f6t\u00fcrmeye \u00e7al\u0131\u015f\u0131yor. \u00d6rne\u011fin, <a href=\"https:\/\/alj.com\/en\/perspective\/democratizing-healthcare-scan-by-scan\/\">el tipi ultrason cihaz\u0131<\/a> Butterfly iQ+, hastal\u0131klar\u0131n daha erken te\u015fhis edilmesini sa\u011flayarak bir\u00e7ok pazarda b\u00fcy\u00fck bir fark yaratabilecek teknolojilere bir \u00f6rnek olarak g\u00f6sterilebilir.<\/p>\r\n\r\n[caption id=\"attachment_94231\" align=\"aligncenter\" width=\"2560\"]<img class=\"size-full wp-image-94231\" src=\"https:\/\/alj.com\/app\/uploads\/2021\/11\/ERM_4668.jpg\" alt=\"Butterfly Network\" width=\"2560\" height=\"1707\" \/> Butterfly IQ+ el tipi, t\u00fcm v\u00fccut i\u00e7in ultrason \u00e7ubu\u011fu \u00e7al\u0131\u015fmakta (Foto\u011fraf Sahibi \u00a9 Butterfly Network Inc.)[\/caption]\r\n\r\n<p>Abdul Latif Jameel\u2019in b\u00f6lgedeki g\u00fc\u00e7l\u00fc miras\u0131, bilgisi, anlay\u0131\u015f\u0131 ve mevcut ortakl\u0131klar\u0131 da bu teknolojileri pazara sunmada ve \u00e7o\u011fu zaman finansal sorunlar kadar k\u00fclt\u00fcrel ve uygulamadaki sorunlar\u0131 da i\u00e7eren baz\u0131 engellerin \u00fcstesinden gelmede b\u00fcy\u00fck bir avantaj sa\u011flayabilir.<\/p>\r\n<h2>\u0130leriye bakt\u0131\u011f\u0131n\u0131zda, kanser ara\u015ft\u0131rmalar\u0131n\u0131n ve kanser tedavisinin gelece\u011fi konusunda ne kadar iyimsersiniz?<\/h2>\r\n<p><strong>CC: <\/strong>Bu konuda tarafs\u0131z olamayabilirim; \u00e7\u00fcnk\u00fc kariyerim boyunca \u00e7al\u0131\u015fmalar\u0131m\u0131 y\u00fcr\u00fctt\u00fc\u011f\u00fcm alanda, meme kanseri tedavi oran\u0131n\u0131n olduk\u00e7a \u00f6nemli \u00f6l\u00e7\u00fcde artt\u0131\u011f\u0131n\u0131 g\u00f6rd\u00fcm. Bu nedenle \u00e7ok iyimserim. Elbette, d\u00fcnya genelinde meme kanseri oranlar\u0131nda h\u00e2l\u00e2 b\u00fcy\u00fck farkl\u0131l\u0131klar var. Yine de genel olarak 10 y\u0131l i\u00e7inde tedavi oranlar\u0131n\u0131 \u00f6nemli \u00f6l\u00e7\u00fcde iyile\u015ftirmi\u015f olaca\u011f\u0131m\u0131z\u0131 umuyorum.<\/p>\r\n<p>\u00d6rne\u011fin akci\u011fer kanseri, pankreas kanseri, beyin kanseri, mide kanseri gibi di\u011fer kanserlerin tedavisi \u00e7ok zordur. Bu durumun nedenlerinden biri de bu kanser t\u00fcrlerinin \u00e7ok ge\u00e7 te\u015fhis edilmesidir. Test, tarama ve erken te\u015fhisle ilgili bu teknolojilerden baz\u0131lar\u0131 hayati \u00f6nemdedir. Bu teknolojileri \u00f6zellikle geli\u015fmekte olan \u00fclkelerde etkili bir \u015fekilde uygulayabilirsek, kanser tedavisinin ilerleyi\u015fini de\u011fi\u015ftirebiliriz.<\/p>\r\n<p>Dedi\u011fim gibi iyimserim ancak bu zamana kadar b\u00f6l\u00fck p\u00f6r\u00e7\u00fck y\u00f6ntemlerle ger\u00e7ekle\u015ftirilen bu uygulamalar\u0131n \u201cend\u00fcstriyel\u201d \u00f6l\u00e7ekte uygulanmas\u0131 gerekiyor.<\/p>"],"_content":[""],"_ame_cpe_post_policy":["{\"accessProtection\":{\"active\":\"replace\"}}"],"_edit_last":["22"],"_wpml_media_duplicate":["1"],"_wpml_media_featured":["1"],"_yoast_wpseo_content_score":["30"],"_yoast_wpseo_estimated-reading-time-minutes":["11"]},"_links":{"self":[{"href":"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/wp-json\/wp\/v2\/perspectives\/15679","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/wp-json\/wp\/v2\/perspectives"}],"about":[{"href":"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/wp-json\/wp\/v2\/types\/perspectives"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/wp-json\/wp\/v2\/media\/15663"}],"wp:attachment":[{"href":"https:\/\/cms.alj3.clients.lemonhq.io\/tr\/wp-json\/wp\/v2\/media?parent=15679"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}